Patients with High-Grade Gliomas Harboring Deletions of Chromosomes 9p and 10q Benefit from Temozolomide Treatment
نویسندگان
چکیده
منابع مشابه
Chromosome 9p and 10q losses predict unfavorable outcome in low-grade gliomas.
The loss of chromosomes 1p-19q is the only prognostic molecular alteration identified in low-grade gliomas (LGGs) to date. Search for loss of heterozygosity (LOH) on chromosomes 1p, 9p, 10q, and 19q was performed in a series of 231 LGGs. Loss of chromosomes 1p-19q was strongly correlated with prolonged progression-free survival (PFS) and overall survival (OS) in univariate and multivariate anal...
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ژورنال
عنوان ژورنال: Neoplasia
سال: 2005
ISSN: 1476-5586
DOI: 10.1593/neo.05307